Research context and placement

Publisher-abstract evidence for defect filling, tissue adhesion and bone repair directly fits tissue–material contact and repair. Cell migration and osteogenic modulation provide a secondary host-interaction link.

Research overview and key contributions

CNC-based triple-network iHEÄLS combines defect filling, tissue adhesion and shape recovery; the abstract reports evaluation in a bone-regeneration model.

Post-crosslinking mechanical training is used to tune the network and biological responses.

Open challenges

Editorial question: How do training history and degradation affect sustained support and regeneration? Clinical efficacy was not verified.

Comparison context

Match defect geometry, tissue/hydration, training direction/cycles, autologous bone mixing and adhesion/regeneration assessment times.

Related external research

Tough adhesives for diverse wet surfaces

DOI: 10.1126/science.aah6362 ↗

The PMC abstract combines an adhesive surface with a dissipative matrix, contrasting this division of interfacial bonding and bulk dissipation with #97's training and defect filling.

This compares wet-adhesion design, not bone-regeneration performance; adhesion energy and bone-formation endpoints are distinct.

Abstract checked

Corresponding-author verification

Jungmok Seo: not a corresponding author

This record concerns Jungmok Seo’s correspondence designation. Author order or an asterisk alone is not treated as confirmation; this check is separate from verification of the research content.

  • Correspondence evidence source ↗

    Corresponding Author — Sang Jin Lee; Corresponding Author — Su Ryon Shin

    Complete author information; Jungmok Seo ordinary-author block and two Corresponding Author blocks · public_publisher_author_information_read

Main-text review scope
The Crossref abstract was read and checked against publisher metadata/abstract: DOI 10.1002/adma.74385, online 2026-08-01. Main text, supplements and quantitative conditions remain unchecked.
Supplementary review scope
Supplementary-information content was not read in this batch. No completed review beyond the previously stated scope is claimed.
Pending verification
Verify training, adhesion, bone-defect models, degradation and supplements in school Chrome. Fabrication protocols and quantitative superiority await verification; figure rights require separate checking.

COVERAGE & OUTREACH

Coverage and outreach

Links are checked for their relationship to this paper. Media publication does not establish independent reporting or additional experimental validation.

  • Niyou Wang · LinkedIn · Date unconfirmed · Researcher-authored post

    Transformative Biomaterial iHEÄLS for Musculoskeletal Repair ↗

    The exact iHEÄLS title, Advanced Materials, authors and mechanical-training/bone-repair description match.

    Body read The public post and linked paper title were read. Only a relative timestamp was shown, so the date is null. This is author promotion, not independent validation.

  • Sang Jin Lee · LinkedIn · Date unconfirmed · Researcher-authored post

    Injectable Hydrogel iHEALS for Bone Regeneration ↗

    The corresponding author links the exact iHEÄLS title and describes shape adaptation and bone regeneration.

    Body read The public post and linked paper title were read. Only a relative timestamp was shown, so the date is null. This is author promotion, not independent validation.

Channel coverage and search log for all 101 records →

Sources and verification scope

The Crossref abstract was read and checked against publisher metadata/abstract: DOI 10.1002/adma.74385, online 2026-08-01. Main text, supplements and quantitative conditions remain unchecked.