Tissue–biomaterial interface. Classification centers on tissue contact, mechanical adaptation and analyte transport.
Designs adhesion, mechanics and molecular transport in tissue-contacting materials to support the contact and access paths needed for sensing or therapy.
Primary assignments in this theme: 20 · Subthemes are editorial proposals for this library. Title-based classification is distinct from full-text verification.
Research centered on bonding to wet tissue and maintaining contact.
Nature Communications, 17, 5526 (2026)
A double-network hydrogel bonds to wet tissue through quinone-mediated interactions. Public-text evidence on patch and injectable applications in animal bleeding and incision models supports placement in wet tissue adhesion.
Advanced Science, 10(30), 2303651 (2023)
The patch centers on conformal adhesion to wet bleeding tissue. Antibacterial and hemostatic behavior supply a secondary biological-interaction connection.
Biotechnology Journal, 16(12), 2100231 (2021)
The abstract explicitly links bioadhesives to tissue adhesion, regeneration and sensing.
Research on compliance, toughness, recovery and swelling in tissue-contacting layers.
Biosensors & Bioelectronics, 255, 116257 (2024)
Modulus control, limited swelling and viscoelasticity address tissue mismatch; Fig. 4 and Methods 2.7–2.9 directly evaluate the porcine-skin interface and adhesion. CNT conduction and stretchable sensing form the secondary routing connection.
Advanced Science, 10(12), 2207237 (2023)
Nanoconfinement couples swelling control, mechanics and conductivity in a tissue-contacting hydrogel. Tissue-adaptive mechanics is the primary theme; electrical transport and adhesion are cross-cutting aspects.
Research on controlling the paths and flux of analytes from tissue or biofluids to a sensing element.
Advanced Materials, 38(19), e15767 (2026)
The gel interface jointly controls transport from biofluids to sensors and mechanical suitability, fitting tissue-coupling analyte transport.
ACS Nano, 12 (2), 932-941 (2018)
Biofluid delivery to assay sites relates to analyte transport; ex vivo droplet handling does not directly establish tissue–material coupling.
Research linking the shape, delivery and fabrication of tissue-contacting materials to tissue repair.
Advanced Materials, e74385 (2026)
Publisher-abstract evidence for defect filling, tissue adhesion and bone repair directly fits tissue–material contact and repair. Cell migration and osteogenic modulation provide a secondary host-interaction link.
Advanced Materials Technologies, 9(11), 2400060 (2024)
Direct delivery of bioinks to wounds and support for cell infiltration establish tissue-repair biofabrication. Robot use alone does not establish electronic component integration.
Materials Science and Engineering R: Reports, 119, 1-35 (2017)
An extended tissue-fabrication grouping; the whole review does not establish direct tissue-contact interface performance.
A provisional grouping for foundational materials or processes that may connect to this theme. It does not establish theme fit; each paper retains a rationale and ambiguity flag.
Advanced Materials Technologies, 9(10), 2400157 (2024)
The ink targets tissue-mimetic mechanics and vessel training models. It is provisionally foundational because these differ from direct living-tissue contact or repair experiments.
Advanced Healthcare Materials, 8 (3), 1801146 (2019)
Foundational tissue mechanics: compression of cardiac fibroblasts in GelMA. The in-vitro fibrosis model is distinct from an implanted-device host response.
Current Pharmaceutical Design, 24 (45), 5458-5470 (2019)
Foundational cell–material screening relates to the tissue interface. In-vitro assays do not establish implanted-device host responses.
ACS Applied Materials & Interfaces, 10 (16), 13293-13303 (2018)
Cell–matrix mechanics is foundational; 3D culture compression does not establish tissue adhesion or implanted-device host response.
Biomaterials, 153, 85-101 (2018)
Foundational cell–material screening review; implantable screening is a future direction in the text, not a demonstrated result.
Nanoscale, 9(47), 18737-18752 (2017)
Foundational cell–material topography/differentiation study; it does not directly establish tissue bonding or chronic implant response.
Biomicrofluidics, 11 (4), 044109 (2017)
Foundational in-vitro liver-toxicity modeling of endothelial barriers and hepatocyte interactions. It does not directly establish tissue repair or implanted-device host responses.
Small, 13 (7), 1602865 (2017)
Foundational analyte delivery; the abstract demonstrates dyes, not direct tissue/biofluid transport.
ACS Applied Materials & Interfaces, 8 (28), 17763-17774 (2016)
Foundational differentiation on culture substrates; functional cell generation is not patient therapy or tissue adhesion.
Advanced Materials, 26 (41), 7043-7050 (2014)
Foundational cell–material research on culture surfaces, stem-cell spheroids and in-vitro angiogenic readouts. In-vivo efficacy and device–host responses are outside the established scope.