Tissue & material
Materials in contact with tissue
How can a material stay in contact with wet, moving tissue? Explore research on adhesion, mechanical adaptation and molecular transport.
20papersMaterials in contact with tissue
BLISS Research Library
Interface engineering for bioelectronics
Explore interface engineering research by Jungmok Seo and BLISS Lab at Yonsei University: hydrogels that adhere to wet tissue, interconnects that carry current under deformation, packaging that joins different materials, and surfaces that control attachment and biological responses. Each summary connects the design and mechanism to observed results, test limitations and the original paper.
01 / EXPLORE THE INTERFACES
Four research themes
Follow the materials, connections and tissue-facing surfaces that make up a bioelectronic device.
Substrate & interconnect
Stretchable conductors and interconnects
How does current travel through materials that bend and stretch? Explore liquid metals, conductive fibers and soft substrates.
Interconnect & chip
Device integration and packaging
How can soft materials and electronic components work as one device? Explore bonding, assembly, insulation and protective packaging.
39papersDevice integration and packaging
Device & host
Biological responses and surface design
What happens when a device meets the body? Explore surfaces that address fouling, friction and interactions with cells and tissue.
Papers are grouped by their main topic, with links to other relevant themes.
02 / RESEARCH
Research to start with
Discover the problem each study addresses, how it approaches it and what it reports. Each paper page includes experimental context and the sources used in the summary.
Quinone-mediated, tissue-adaptive double-network hydrogel for instant hemostasis and wet-tissue adhesion
Nature Communications, 17, 5526 (2026)
STAT, a quinone-mediated double-network hydrogel, bonded to wet porcine skin at 273 kPa lap-shear strength and stopped mouse liver bleeding within 10 s.
Bioadaptive liquid-infused multifunctional fibers for long-term neural recording via BDNF stabilization and enhanced neural interaction
Science Advances, 11(37), eadz1228 (2025)
TAB combines a lubricated interface with immobilized BDNF to reduce nonspecific attachment and support neuronal interactions. Representative single-unit recordings in mice extend to 12 months; electrode-level statistical comparisons cover a separate 8-month period.
Universal hydrogel adhesives with robust chain entanglement for bridging soft electronic materials
npj Flexible Electronics, 8, 39 (2024)
d-HAPT joins dissimilar electronic materials through moisture-induced chain entanglement in dried PVA–tannic acid layers. Dry–dry bonding uses interfacial water and heat; wet–dry bonding uses hydrogel moisture. Wet–wet and dry-material–tissue adhesion remain limited.
Postoperative Long-Term Monitoring of Mechanical Characteristics in Reconstructed Soft Tissues Using Biocompatible, Immune-Tolerant, and Wireless Electronic Sutures
ACS Nano, 18(19), 12210-12224 (2024)
A wireless, chip-less strain-sensing suture followed a reconstructed porcine Achilles tendon for 10 weeks; strain fell to 5.83% (normal tendon: 4.38%).
Functionalized EGaIn Electrodes with Tunable Reduced‐Graphene‐Oxide Assembled EGaIn Core–Shell Particles for Soft and Deformable Electrochemical Biosensors
Advanced Functional Materials, 34(31), 2311696 (2024)
Stretchable liquid-metal electrodes coated with rGO-wrapped EGaIn particles resolved ascorbic acid, dopamine and uric acid peaks after 200 cycles of 30% strain.
Intrinsically Nonswellable Multifunctional Hydrogel with Dynamic Nanoconfinement Networks for Robust Tissue‐Adaptable Bioelectronics
Advanced Science, 10(12), 2207237 (2023)
A PVA/PAA hydrogel with tannic acid and carbon nanotube nanoconfinement resisted swelling, self-healed within 5 min, conducted ≈40 S m−1 and was 3D printable.
Antibacterial infection and immune-evasive coating for orthopedic implants
Science Advances, 6 (44), eabb0025 (2020)
A lubricant-infused stainless-steel implant coating prevented infection in all six rabbits given MRSA-preincubated fixation implants, versus six of six bare.
Ag Nanowire Reinforced Highly Stretchable Conductive Fibers for Wearable Electronics
Advanced Functional Materials, 25 (21), 3114-3121 (2015)
Silver nanowires inside wet-spun SBS fibres bridged silver nanoparticle networks, keeping conduction up to 220% strain; a five-fibre glove read sign letters.
03 / BEYOND THE PAPER
Research stories and news
Read university announcements, news articles and publisher features alongside the papers they discuss.
Explore research storiesAbout this library